A prime gap of length 
 is a run of 
 consecutive composite numbers between two successive
 primes. Therefore, the difference between two successive primes 
 and 
 bounding a prime gap of length 
 is 
,
 where 
 is the 
th prime number. Since the
 prime difference function
| 
 
(1)
 
 | 
is always even (except for ),
 all primes gaps 
 are also even. The notation 
 is commonly used to denote the smallest prime 
 corresponding to the start of a prime gap of length 
, i.e., such that 
 is prime, 
, 
, ..., 
 are all composite, and 
 is prime (with the additional constraint that
 no smaller number satisfying these properties exists).
The maximal prime gap 
 is the length of the largest prime gap that begins with a prime 
 less than some maximum value 
. For 
,
 2, ..., 
 is given by 4, 8, 20, 36, 72, 114, 154, 220, 282, 354, 464, 540, 674, 804, 906, 1132,
 ... (OEIS A053303).
Arbitrarily large prime gaps exist. For example, for any , the numbers 
, 
,
 ..., 
 are all composite (Havil 2003, p. 170).
 However, no general method more sophisticated than an exhaustive search is known
 for the determination of first occurrences and maximal prime gaps (Nicely 1999).
Cramér (1937) and Shanks (1964) conjectured that
| 
 
(2)
 
 | 
Wolf conjectures a slightly different form
| 
 
(3)
 
 | 
which agrees better with numerical evidence.
Wolf conjectures that the maximal gap  between two consecutive primes less than 
 appears approximately at
| 
 
(4)
 
 | 
where  is the prime
 counting function and 
 is the twin primes constant. Setting 
 reduces to Cramer's conjecture
 for large 
,
| 
 
(5)
 
 | 
It is known that there is a prime gap of length 803 following , and a prime gap of length 
 following 
 (Baugh and O'Hara 1992). H. Dubner (2001)
 discovered a prime gap of length 
 between two 3396-digit probable
 primes. On Jan. 15, 2004, J. K. Andersen and H. Rosenthal
 found a prime gap of length 
 between two probabilistic primes of 
 digits each. In January-May 2004, Hans Rosenthal and Jens
 Kruse Andersen found a prime gap of length 
 between two probabilistic primes with 
 digits each (Anderson 2004).
The merit of a prime gap compares the size of a gap to the local average gap, and is given by .
 In 1999, the number 1693182318746371 was found, with merit 
. This remained the record merit until 804212830686677669
 was found in 2005, with a gap of 1442 and a merit of 
. Andersen maintains a list of the top 20 known merits.
 The prime gaps of increasing merit are 2, 3, 7, 113, 1129, 1327, 19609, ... (OEIS
 A111870).
Young and Potler (1989) determined the first occurrences of prime gaps up to , with all first occurrences
 found between 1 and 673. Nicely (1999) has extended the list of maximal prime gaps.
 The following table gives the values of 
 for small 
, omitting degenerate runs which are part of a run with greater
 
 (OEIS A005250
 and A002386).
| 1 | 2 | 354 | |
| 2 | 3 | 382 | |
| 4 | 7 | 384 | |
| 6 | 23 | 394 | |
| 8 | 89 | 456 | |
| 14 | 113 | 464 | |
| 18 | 523 | 468 | |
| 20 | 887 | 474 | |
| 22 | 486 | ||
| 34 | 490 | ||
| 36 | 500 | ||
| 44 | 514 | ||
| 52 | 516 | ||
| 72 | 532 | ||
| 86 | 534 | ||
| 96 | 540 | ||
| 112 | 582 | ||
| 114 | 588 | ||
| 118 | 602 | ||
| 132 | 652 | ||
| 148 | 674 | ||
| 154 | 716 | ||
| 180 | 766 | ||
| 210 | 778 | ||
| 220 | 804 | ||
| 222 | 806 | ||
| 234 | 906 | ||
| 248 | 916 | ||
| 250 | 924 | ||
| 282 | |||
| 288 | |||
| 292 | |||
| 320 | |||
| 336 | 
Define
| 
 
(6)
 
 | 
as the infimum limit of the ratio of the th prime difference to the natural
 logarithm of the 
th
 prime number. If there are an infinite number of twin
 primes, then 
.
 This follows since it must then be true that 
 infinitely often, say at 
 for 
, 2, ..., so a necessary condition
 for the twin prime conjecture to hold is
 that
| 
 
(7)
 
 | |||
| 
 
(8)
 
 | |||
| 
 
(9)
 
 | |||
| 
 
(10)
 
 | 
However, this condition is not sufficient, since the same proof works if 2 is replaced by any constant.
Hardy and Littlewood showed in 1926 that, subject to the truth of the generalized Riemann hypothesis, .
 This was subsequently improved by Rankin (again assuming the generalized Riemann
 hypothesis) to 
.
 In 1940, Erdős used sieve theory to show for the first time with no assumptions
 that 
. This was subsequently improved
 to 15/16 (Ricci), 
 (Bombieri and Davenport 1966), and 
 (Pil'Tai 1972), as quoted in Le Lionnais
 (1983, p. 26). Huxley (1973, 1977) obtained 
, which was improved by Maier in 1986 to
 
, which was the best result
 known until 2003 (American Institute of Mathematics).
At a March 2003 meeting on elementary and analytic number theory in Oberwolfach, Germany, Goldston and Yildirim presented an attempted proof that . While the original proof turned out to be flawed (Mackenzie
 2003ab), the result has now been established by a new proof (American Institute of
 Mathematics 2005, Cipra 2005, Devlin 2005, Goldston et al. 2005ab).